Results of a Completed Phase 1 Study of LAM-002 (Apilimod Dimesylate), a First-in-Class Phosphatidylinositol-3-Phosphate 5 Kinase (PIKfyve) Inhibitor, Administered as Monotherapy or With Rituximab or Atezolizumab to Patients with Previously Treated Follicular Lymphoma or Other B-cell Cancers
Catherine S Diefenbach, Jonathon B Cohen, Wael A Harb, Stephen M Ansell, Loretta J Nastoupil, Jeremy S Abramson, Nehal J Lakhani, Marshall T Schreeder, Taimur Sher, Dipti Patel-Donnelly, David M Aboulafia, Candace Fuchs, Darrell Nix, Sean Landrette, Patricia S Graham, Lydia B King, Peter R Young, Langdon L Miller, Henri Lichenstein, Sarah C Rutherford
Efficacy and Safety of Topical Rapamycin in Patients With Facial Angiofibromas Secondary to Tuberous Sclerosis Complex
Mary Kay Koenig, Cynthia S. Bell, Adelaide A. Hebert, Joan Roberson, Joshua A. Samuels, John M. Slopis, Patti Tate, Hope Northrup
LAM-003, a Novel Oral Heat Shock Protein 90 Inhibitor for Treatment of Acute Myeloid Leukemia, Including Wild-Type and FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Disease
Neil Beeharry, Sean Landrette, Jeff Grotzke, Sophia Gayle, Marylens Hernandez, Stephanie Halene, Peter Young, Langdon Miller, Tian Xu, Jonathan Rothberg, Henri Lichenstein
LAM-003, a new drug for treatment of tyrosine kinase inhibitor–resistant FLT3-ITD–positive AML
Neil Beeharry, Sean Landrette, Sophia Gayle, Marylens Hernandez, Jeff E. Grotzke, Peter R. Young, Paul Beckett, Xuan Zhang, Bing Z. Carter, Michael Andreeff, Stephanie Halene, Tian Xu, Jonathan Rothberg, Henri Lichenstein
Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma
Sophia Gayle, Sean Landrette, Neil Beeharry, Chris Conrad, Marylens Hernandez, Paul Beckett, Shawn M. Ferguson, Talya Mandelkern, Meiling Zheng, Tian Xu, Jonathan Rothberg and Henri Lichenstein
Phase 1 Clinical Safety, Pharmacokinetics (PK), and Activity of Apilimod Dimesylate (LAM-002A), a First-in-Class Inhibitor of Phosphatidylinositol-3-Phosphate 5-Kinase (PIKfyve), in Patients with Relapsed or Refractory B-Cell Malignancies
Wael A Harb, Catherine S Diefenbach, Nehal Lakhani, Sarah C Rutherford, Marshall T Schreeder, Stephen M. Ansell, Taimur Sher, David M Aboulafia, Jonathon B Cohen, Darrell Nix, Sean Landrette, Kate Flanders, Langdon L Miller, Henri Lichenstein and Jeremy S. Abramson
